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Assay Detail

CHEMBL3096576

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PDE3B (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (CHEMBL290)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example.
Boehm M, Hepworth D, Loria PM, Norquay LD, Filipski KJ, Chin JE, Cameron KO, Brenner M, Bonnette P, Cabral S, Conn E, Ebner DC, Gautreau D, Hadcock J, Lee EC, Mathiowetz AM, Morin M, Rogers L, Smith A, VanVolkenburg M, Carpino PA.
ACS Med Chem Lett (2013) 4 : 1079 -1084
PubMed 24900608 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.62 4.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3092413 1 4.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3092413 IC50 = 24000.0 nM 4.62