Assay Detail
ADMET
CHEMBL3097552
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Cytotoxicity against human WI38 cells after 72 hrs by Alamar Blue assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | WI-38 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Secoemestrin D, a cytotoxic epitetrathiodioxopiperizine, and emericellenes A-E, five sesterterpenoids from Emericella sp. AST0036, a fungal endophyte of Astragalus lentiginosus1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.62 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3092735 | — | — | 1 | 6.62 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | - |
| CHEMBL524291 | STERIGMATOCYSTIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3092735 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL53463 | DOXORUBICIN | IC50 | - | — | - | |
| CHEMBL524291 | STERIGMATOCYSTIN | IC50 | - | — | - |