Assay Detail
Binding
CHEMBL3097753
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Dual specificity protein kinase CLK2 (CHEMBL1075281) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Chemical synthesis and biological validation of immobilized protein kinase inhibitory Leucettines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.58 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3092863 | — | — | 1 | 6.68 |
| CHEMBL3092862 | — | — | 1 | 6.55 |
| CHEMBL1802358 | — | — | 1 | 6.50 |
| CHEMBL3092864 | — | — | 1 | - |
| CHEMBL3092861 | — | — | 1 | - |
| CHEMBL3092860 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3092863 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL3092862 | — | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL1802358 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL3092864 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3092861 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3092860 | — | IC50 | > | 10000.0 | nM | - |