Assay Detail
Functional
CHEMBL3100349
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Cytotoxicity against rat C6 cells after 72 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | C6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antitumor potential of conjugable valinomycins bearing hydroxyl sites: in vitro studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.33 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL223643 | VALINOMYCIN | — | 1 | 9.40 |
| CHEMBL3099816 | — | — | 1 | 8.62 |
| CHEMBL3099598 | — | — | 1 | 8.54 |
| CHEMBL3099817 | — | — | 1 | 6.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL223643 | VALINOMYCIN | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL3099816 | — | IC50 | = | 2.4 | nM | 8.62 |
| CHEMBL3099598 | — | IC50 | = | 2.9 | nM | 8.54 |
| CHEMBL3099817 | — | IC50 | = | 175.2 | nM | 6.76 |