Assay Detail

CHEMBL3106930

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Reduction of triglyceride AUC in human

ChEMBL ↗

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Target

Homo sapiens (CHEMBL372) ↗

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Primary target Homo sapiens

CHEMBL372

Anchored from Assay target.

Protein identity Homo sapiens

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Confidence	1 — Organism
Curated By	Autocuration

Target

Homo sapiens (CHEMBL372) ↗

Type	ORGANISM
Organism	Homo sapiens

Publication

Current status of the research and development of diacylglycerol O-acyltransferase 1 (DGAT1) inhibitors.

DeVita RJ, Pinto S.
J Med Chem (2013) 56 : 9820 -9825
PubMed 23919406 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	6.36	6.36

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4297354	AZD-7687	1.0	1	6.36

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4297354	AZD-7687	EC50	=	440.0	nM	6.36