Assay Detail
Binding
CHEMBL3108313
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant HDAC10 (unknown origin) using Fluor-de-Lys-SIRT1 as substrate by fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.78 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 7.16 |
| CHEMBL3104855 | — | — | 1 | 5.09 |
| CHEMBL3104851 | — | — | 1 | 5.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL3104855 | — | IC50 | = | 8100.0 | nM | 5.09 |
| CHEMBL3104851 | — | IC50 | = | 8400.0 | nM | 5.08 |