Assay Detail
Binding
CHEMBL3108328
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Inhibition of ARK5 (unknown origin)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.66 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL388978 | STAUROSPORINE | — | 1 | 8.10 |
| CHEMBL3104851 | — | — | 1 | 5.60 |
| CHEMBL3104855 | — | — | 1 | 5.42 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 5.29 |
| CHEMBL3104854 | — | — | 1 | 5.00 |
| CHEMBL3104852 | — | — | 1 | 4.53 |
| CHEMBL3104853 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL388978 | STAUROSPORINE | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL3104851 | — | IC50 | = | 2510.0 | nM | 5.60 |
| CHEMBL3104855 | — | IC50 | = | 3770.0 | nM | 5.42 |
| CHEMBL50 | QUERCETIN | IC50 | = | 5090.0 | nM | 5.29 |
| CHEMBL3104854 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL3104852 | — | IC50 | = | 29800.0 | nM | 4.53 |
| CHEMBL3104853 | — | IC50 | > | 30000.0 | nM | - |