NUAK family SNF1-like kinase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt O60285. Use UniProt O60285 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O60285 as the stable identity anchor, then attach disease evidence before program review.
NUAK family SNF1-like kinase 1
Review this target as NUAK family SNF1-like kinase 1, mapped to UniProt O60285. Sequence length is 661 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats NUAK family SNF1-like kinase 1 as ChEMBL target CHEMBL5784, mapped to UniProt O60285. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | NUAK family SNF1-like kinase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O60285 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | NUAK family SNF1-like kinase 1 |
| UniProt Accession | O60285 |
| Component Type | Protein |
| Sequence Length | 661 aa |
NUAK family SNF1-like kinase 1
Review this target as NUAK family SNF1-like kinase 1, mapped to UniProt O60285. Sequence length is 661 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 8.88 | IC50 | 1.31 | Preclinical |
| CHEMBL5176650 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL4303523 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL5303523 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL1908392 | 8.77 | Ki | 1.7 | Preclinical |
| CHEMBL3780091 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5199998 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL5305160 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL5173501 | 8.43 | IC50 | 3.7 | Preclinical |
| CHEMBL603469 | 8.43 | Kd | 3.7 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 265 | 74 | 6.8 |
| assay format | 37 | 21 | 7.6 |
| cell-based format | 30 | 11 | 7.3 |
| subcellular format | 1 | 0 | — |