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Assay Detail

CHEMBL3110533

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Binding
Binding affinity to His-tagged STAT3 (unknown origin) by SPR spectroscopic analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Signal transducer and activator of transcription 3 (CHEMBL4026)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma.
Haftchenary S, Luchman HA, Jouk AO, Veloso AJ, Page BD, Cheng XR, Dawson SS, Grinshtein N, Shahani VM, Kerman K, Kaplan DR, Griffin C, Aman AM, Al-Awar R, Weiss S, Gunning PT.
ACS Med Chem Lett (2013) 4 : 1102 -1107
PubMed 24900612 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3108909 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3108909 Kd = 300.0 nM 6.52