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Assay Detail

CHEMBL3110609

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human Calu6 cells assessed as cell viability after 72 hrs by MTS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Calu-6
Confidence 1 — Organism
Curated By Autocuration

Publication

Synthesis and evaluation of novel cyclic Peptide inhibitors of lysine-specific demethylase 1.
Kumarasinghe IR, Woster PM.
ACS Med Chem Lett (2014) 5 : 29 -33
PubMed 24883177 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.96 4.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL378900 1 4.96
CHEMBL3108897 1 -
CHEMBL3108899 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL378900 IC50 = 10900.0 nM 4.96
CHEMBL3108897 IC50 = 125300.0 nM -
CHEMBL3108899 IC50 = 120700.0 nM -