Assay Detail
Binding
CHEMBL3118782
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Inhibition of Trichomonas vaginalis uridine nucleoside ribohydrolase using 5-fluorouridine as substrate after 40 mins by NMR spectrometric analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Trichomonas vaginalis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.67 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1219 | RABEPRAZOLE | 4.0 | 1 | 6.52 |
| CHEMBL1503 | OMEPRAZOLE | 4.0 | 1 | 5.64 |
| CHEMBL3989559 | PANTOPRAZOLE SODIUM | 4.0 | 1 | 4.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1219 | RABEPRAZOLE | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL1503 | OMEPRAZOLE | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL3989559 | PANTOPRAZOLE SODIUM | IC50 | = | 14500.0 | nM | 4.84 |