Assay Detail
Functional
CHEMBL3129228
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Antimycobacterial activity against Mycobacterium bovis BCG after 5 days by MTT assay
82
Total Activities
82
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mycobacterium tuberculosis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, cytostatic, antimicrobial, and anti-HCV activity of 6-substituted 7-(het)aryl-7-deazapurine ribonucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 82 | 4.63 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1269812 | — | — | 1 | 6.52 |
| CHEMBL3126913 | — | — | 1 | 5.68 |
| CHEMBL3126886 | — | — | 1 | 5.61 |
| CHEMBL1814768 | — | — | 1 | 5.33 |
| CHEMBL3126888 | — | — | 1 | 5.07 |
| CHEMBL3126909 | — | — | 1 | 5.03 |
| CHEMBL3126910 | — | — | 1 | 4.85 |
| CHEMBL1814767 | — | — | 1 | 4.76 |
| CHEMBL3126911 | — | — | 1 | 4.73 |
| CHEMBL3127044 | — | — | 1 | 4.68 |
| CHEMBL3126889 | — | — | 1 | 4.61 |
| CHEMBL3126912 | — | — | 1 | 4.58 |
| CHEMBL3126908 | — | — | 1 | 4.41 |
| CHEMBL3126914 | — | — | 1 | 4.37 |
| CHEMBL3126915 | — | — | 1 | 4.29 |
| CHEMBL3126885 | — | — | 1 | 4.15 |
| CHEMBL3127046 | — | — | 1 | 4.13 |
| CHEMBL3126884 | — | — | 1 | 4.08 |
| CHEMBL3126892 | — | — | 1 | 4.08 |
| CHEMBL3127057 | — | — | 1 | 4.06 |
| CHEMBL3126898 | — | — | 1 | 4.06 |
| CHEMBL3127052 | — | — | 1 | 4.01 |
| CHEMBL3127056 | — | — | 1 | 4.01 |
| CHEMBL319177 | — | — | 1 | 4.00 |
| CHEMBL3126901 | — | — | 1 | - |
| CHEMBL3127059 | — | — | 1 | - |
| CHEMBL3127060 | — | — | 1 | - |
| CHEMBL3127061 | — | — | 1 | - |
| CHEMBL3127062 | — | — | 1 | - |
| CHEMBL3127063 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1269812 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL3126913 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL3126886 | — | IC50 | = | 2440.0 | nM | 5.61 |
| CHEMBL1814768 | — | IC50 | = | 4730.0 | nM | 5.33 |
| CHEMBL3126888 | — | IC50 | = | 8530.0 | nM | 5.07 |
| CHEMBL3126909 | — | IC50 | = | 9300.0 | nM | 5.03 |
| CHEMBL3126910 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL1814767 | — | IC50 | = | 17400.0 | nM | 4.76 |
| CHEMBL3126911 | — | IC50 | = | 18500.0 | nM | 4.73 |
| CHEMBL3127044 | — | IC50 | = | 20800.0 | nM | 4.68 |
| CHEMBL3126889 | — | IC50 | = | 24600.0 | nM | 4.61 |
| CHEMBL3126912 | — | IC50 | = | 26500.0 | nM | 4.58 |
| CHEMBL3126908 | — | IC50 | = | 38900.0 | nM | 4.41 |
| CHEMBL3126914 | — | IC50 | = | 42900.0 | nM | 4.37 |
| CHEMBL3126915 | — | IC50 | = | 51400.0 | nM | 4.29 |
| CHEMBL3126885 | — | IC50 | = | 71500.0 | nM | 4.15 |
| CHEMBL3127046 | — | IC50 | = | 73500.0 | nM | 4.13 |
| CHEMBL3126892 | — | IC50 | = | 82700.0 | nM | 4.08 |
| CHEMBL3126884 | — | IC50 | = | 84000.0 | nM | 4.08 |
| CHEMBL3127057 | — | IC50 | = | 87100.0 | nM | 4.06 |
| CHEMBL3126898 | — | IC50 | = | 87100.0 | nM | 4.06 |
| CHEMBL3127052 | — | IC50 | = | 98600.0 | nM | 4.01 |
| CHEMBL3127056 | — | IC50 | = | 96800.0 | nM | 4.01 |
| CHEMBL319177 | — | IC50 | = | 99900.0 | nM | 4.00 |
| CHEMBL3127065 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127045 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3126906 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127058 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127055 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127054 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127053 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127051 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127050 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127049 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127048 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL403715 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127047 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3126905 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3126904 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3126903 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3126902 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3126900 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3126899 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127064 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127063 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127062 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127061 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127060 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3127059 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3126901 | — | IC50 | > | 100000.0 | nM | - |