Assay Detail
Binding
CHEMBL3131238
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Inhibition of Pseudomonas aeruginosa FabH after 25 mins
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas aeruginosa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design and synthesis of 2-styryl of 5-Nitroimidazole derivatives and antimicrobial activities as FabH inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.83 | 5.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1384 | KANAMYCIN | 4.0 | 1 | 5.17 |
| CHEMBL3127243 | — | — | 1 | 5.10 |
| CHEMBL3127242 | — | — | 1 | 4.99 |
| CHEMBL3127229 | — | — | 1 | 4.91 |
| CHEMBL3127232 | — | — | 1 | 4.80 |
| CHEMBL3127233 | — | — | 1 | 4.72 |
| CHEMBL3127226 | — | — | 1 | 4.65 |
| CHEMBL3127238 | — | — | 1 | 4.59 |
| CHEMBL3127234 | — | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1384 | KANAMYCIN | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL3127243 | — | IC50 | = | 7900.0 | nM | 5.10 |
| CHEMBL3127242 | — | IC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL3127229 | — | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL3127232 | — | IC50 | = | 15900.0 | nM | 4.80 |
| CHEMBL3127233 | — | IC50 | = | 19200.0 | nM | 4.72 |
| CHEMBL3127226 | — | IC50 | = | 22500.0 | nM | 4.65 |
| CHEMBL3127238 | — | IC50 | = | 25600.0 | nM | 4.59 |
| CHEMBL3127234 | — | IC50 | = | 29200.0 | nM | 4.54 |