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Assay Detail

CHEMBL3132069

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to 5HT4 receptor in guinea pig distal colon
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 4 (CHEMBL5017)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Synthesis and biological evaluation of positron emission tomography radiotracers targeting serotonin 4 receptors in brain: [18F]MNI-698 and [18F]MNI-699.
Caillé F, Morley TJ, Tavares AA, Papin C, Twardy NM, Alagille D, Lee HS, Baldwin RM, Seibyl JP, Barret O, Tamagnan GD.
Bioorg Med Chem Lett (2013) 23 : 6243 -6247
PubMed 24157369 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 10.70 10.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL68131 1 10.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL68131 Kd = 0.02 nM 10.70