Assay Detail
Functional
CHEMBL3135121
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Cytotoxicity against human MOLT3 cells by XTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MOLT-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Flavans from Desmos cochinchinensis as potent aromatase inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.77 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL44657 | ETOPOSIDE | 4.0 | 1 | 7.52 |
| CHEMBL3134109 | — | — | 1 | 4.61 |
| CHEMBL3134114 | — | — | 1 | 4.54 |
| CHEMBL3134113 | — | — | 1 | 4.53 |
| CHEMBL3134112 | — | — | 1 | 4.38 |
| CHEMBL3134110 | — | — | 1 | 4.24 |
| CHEMBL3134111 | — | — | 1 | 4.20 |
| CHEMBL53343 | — | — | 1 | 4.14 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | - |
| CHEMBL3134115 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL44657 | ETOPOSIDE | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL3134109 | — | IC50 | = | 24330.0 | nM | 4.61 |
| CHEMBL3134114 | — | IC50 | = | 28480.0 | nM | 4.54 |
| CHEMBL3134113 | — | IC50 | = | 29810.0 | nM | 4.53 |
| CHEMBL3134112 | — | IC50 | = | 41270.0 | nM | 4.38 |
| CHEMBL3134110 | — | IC50 | = | 57410.0 | nM | 4.24 |
| CHEMBL3134111 | — | IC50 | = | 63500.0 | nM | 4.20 |
| CHEMBL53343 | — | IC50 | = | 71980.0 | nM | 4.14 |
| CHEMBL53463 | DOXORUBICIN | IC50 | - | — | - | |
| CHEMBL3134115 | — | IC50 | - | — | - |