Assay Detail

CHEMBL3136101

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Agonist activity at human ER-beta transfected in HEK293 cells after 48 hrs by luciferase reporter gene assay

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

Estrogen receptor beta (CHEMBL242) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

Estrogen receptor beta (CHEMBL242) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Estrogen receptor beta

CHEMBL242

Anchored from Assay target.

Protein identity Estrogen receptor beta

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Cell Type	HEK293
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Estrogen receptor beta (CHEMBL242) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

The A-CD analogue of 16,17-estriol is a potent and highly selective estrogen receptor agonist

Sauvee C, Schafer A, Sunden H, Ma J, Gustavsson A, Burstein ES, Olsson R
Medchemcomm (2013) 4 : 1439 -1442
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	7.70	7.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL44	GENISTEIN	2.0	1	7.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL44	GENISTEIN	EC50	=	19.95	nM	7.70