Assay Detail
Binding
CHEMBL3136675
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to L3MBTL1 (unknown origin) by isothermal titration calorimetric analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Lethal(3)malignant brain tumor-like protein 1 (CHEMBL1287622) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 4.76 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3134126 | — | — | 1 | 5.48 |
| CHEMBL3134131 | — | — | 1 | 4.72 |
| CHEMBL3134146 | — | — | 1 | 4.52 |
| CHEMBL3134141 | — | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3134126 | — | Kd | = | 3300.0 | nM | 5.48 |
| CHEMBL3134131 | — | Kd | = | 19000.0 | nM | 4.72 |
| CHEMBL3134146 | — | Kd | = | 30000.0 | nM | 4.52 |
| CHEMBL3134141 | — | Kd | = | 48000.0 | nM | 4.32 |