Assay Detail
Binding
CHEMBL3137185
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Inhibition of human recombinant CYP1A2 after 15 mins by 7-ethoxyresorufin-O-deethylation-based spectrofluorimetry
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
3,4,2-Trimethoxy-trans-stilbene a potent CYP1B1 inhibitor
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.28 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3132928 | — | — | 1 | 5.64 |
| CHEMBL3132924 | — | — | 1 | 5.48 |
| CHEMBL327223 | — | — | 1 | 5.22 |
| CHEMBL3132925 | — | — | 1 | 4.79 |
| CHEMBL3132931 | — | — | 1 | - |
| CHEMBL3132930 | — | — | 1 | - |
| CHEMBL3132929 | — | — | 1 | - |
| CHEMBL3132927 | — | — | 1 | - |
| CHEMBL3132926 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3132928 | — | IC50 | = | 2310.0 | nM | 5.64 |
| CHEMBL3132924 | — | IC50 | = | 3320.0 | nM | 5.48 |
| CHEMBL327223 | — | IC50 | = | 6040.0 | nM | 5.22 |
| CHEMBL3132925 | — | IC50 | = | 16020.0 | nM | 4.79 |
| CHEMBL3132931 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3132930 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3132929 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3132927 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3132926 | — | IC50 | > | 100000.0 | nM | - |