Assay Detail
Binding
CHEMBL3137186
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Inhibition of human recombinant CYP1A1 after 15 mins by 7-ethoxyresorufin-O-deethylation-based spectrofluorimetry
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
3,4,2-Trimethoxy-trans-stilbene a potent CYP1B1 inhibitor
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.22 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3132928 | — | — | 1 | 6.64 |
| CHEMBL3132931 | — | — | 1 | 6.57 |
| CHEMBL3132924 | — | — | 1 | 6.44 |
| CHEMBL327223 | — | — | 1 | 6.36 |
| CHEMBL3132925 | — | — | 1 | 6.35 |
| CHEMBL3132927 | — | — | 1 | 6.30 |
| CHEMBL3132926 | — | — | 1 | 6.29 |
| CHEMBL3132930 | — | — | 1 | 5.75 |
| CHEMBL3132929 | — | — | 1 | 5.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3132928 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL3132931 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL3132924 | — | IC50 | = | 360.0 | nM | 6.44 |
| CHEMBL327223 | — | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL3132925 | — | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL3132927 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL3132926 | — | IC50 | = | 510.0 | nM | 6.29 |
| CHEMBL3132930 | — | IC50 | = | 1780.0 | nM | 5.75 |
| CHEMBL3132929 | — | IC50 | = | 5180.0 | nM | 5.29 |