Assay Detail
Functional
CHEMBL3214984
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PubChem BioAssay. Medium Throughput Quantitative RT-PCR for CHOP Gene Expression. (Class of assay: confirmatory)
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | confirmatory |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
DNA damage-inducible transcript 3 protein (CHEMBL2146304) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.29 | 5.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1555935 | — | — | 1 | 5.54 |
| CHEMBL1582448 | — | — | 1 | 5.45 |
| CHEMBL1405952 | — | — | 1 | 5.43 |
| CHEMBL1578584 | — | — | 1 | 5.36 |
| CHEMBL1900850 | — | — | 1 | 5.34 |
| CHEMBL1392142 | — | — | 1 | 5.21 |
| CHEMBL1573994 | — | — | 1 | 5.21 |
| CHEMBL3185655 | — | — | 1 | 4.74 |
| CHEMBL1507250 | — | — | 1 | - |
| CHEMBL1537098 | — | — | 1 | - |
| CHEMBL1576870 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1555935 | — | IC50 | = | 2890.0 | nM | 5.54 |
| CHEMBL1582448 | — | IC50 | = | 3580.0 | nM | 5.45 |
| CHEMBL1405952 | — | IC50 | = | 3730.0 | nM | 5.43 |
| CHEMBL1578584 | — | IC50 | = | 4370.0 | nM | 5.36 |
| CHEMBL1900850 | — | IC50 | = | 4530.0 | nM | 5.34 |
| CHEMBL1392142 | — | IC50 | = | 6120.0 | nM | 5.21 |
| CHEMBL1573994 | — | IC50 | = | 6180.0 | nM | 5.21 |
| CHEMBL3185655 | — | IC50 | = | 18370.0 | nM | 4.74 |
| CHEMBL1507250 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL1537098 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL1576870 | — | IC50 | > | 20000.0 | nM | - |