Assay Detail
Functional
CHEMBL3222528
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against ER positive human MCF10AT1 cells after 3 days by [3H]thymidine uptake assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure-function study of gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.11 | 9.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3220717 | — | — | 1 | 9.64 |
| CHEMBL3220718 | — | — | 1 | 9.29 |
| CHEMBL846 | CALCITRIOL | 4.0 | 1 | 8.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3220717 | — | IC50 | = | 0.23 | nM | 9.64 |
| CHEMBL3220718 | — | IC50 | = | 0.51 | nM | 9.29 |
| CHEMBL846 | CALCITRIOL | IC50 | = | 3.9 | nM | 8.41 |