Assay Detail
Binding
CHEMBL3223598
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Inhibition of PI3K (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Small molecules targeting phosphoinositide 3-kinases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.79 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL411907 | SONOLISIB | 2.0 | 1 | 10.00 |
| CHEMBL273832 | — | — | 1 | 9.30 |
| CHEMBL428496 | WORTMANNIN | — | 1 | 8.38 |
| CHEMBL98350 | LY-294002 | -1.0 | 1 | 5.85 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 5.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL411907 | SONOLISIB | IC50 | = | 0.1 | nM | 10.00 |
| CHEMBL273832 | — | IC50 | = | 0.5 | nM | 9.30 |
| CHEMBL428496 | WORTMANNIN | IC50 | = | 4.2 | nM | 8.38 |
| CHEMBL98350 | LY-294002 | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL50 | QUERCETIN | IC50 | = | 3800.0 | nM | 5.42 |