Assay Detail
Binding
CHEMBL3223623
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EGFR (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Small molecules targeting phosphoinositide 3-kinases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.17 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1081312 | — | — | 1 | 6.58 |
| CHEMBL1234815 | — | — | 1 | 6.41 |
| CHEMBL1233882 | — | — | 1 | 6.21 |
| CHEMBL1230790 | — | — | 1 | 6.02 |
| CHEMBL1233881 | — | — | 1 | 5.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1081312 | — | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL1234815 | — | IC50 | = | 388.0 | nM | 6.41 |
| CHEMBL1233882 | — | IC50 | = | 610.0 | nM | 6.21 |
| CHEMBL1230790 | — | IC50 | = | 954.0 | nM | 6.02 |
| CHEMBL1233881 | — | IC50 | = | 2300.0 | nM | 5.64 |