Assay Detail

CHEMBL3225115

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Functional

Cytotoxicity against human MOLT3 cells

ChEMBL ↗

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Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

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NON-PROTEIN TARGET (CHEMBL3879801) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target NON-PROTEIN TARGET

CHEMBL3879801

Anchored from Assay target.

Protein identity NON-PROTEIN TARGET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	MOLT-3
Confidence	1 — Organism
Curated By	Autocuration

Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Type	NON-MOLECULAR

Publication

Diaryl ether derivatives as anticancer agents a review

Bedos-Belval F, Rouch A, Vanucci-Bacque C, Baltas M
Medchemcomm (2012) 3 : 1356 -1372
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	6.78	7.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL44657	ETOPOSIDE	4.0	1	7.70
CHEMBL3221176	—	—	1	5.85

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL44657	ETOPOSIDE	IC50	=	20.0	nM	7.70
CHEMBL3221176	—	IC50	=	1400.0	nM	5.85