Assay Detail
Binding
CHEMBL3225121
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Inhibition of MMP-1 (unknown origin)
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Diaryl ether derivatives as anticancer agents a review
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.05 | 5.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2115165 | — | — | 1 | 5.05 |
| CHEMBL3221177 | — | — | 1 | - |
| CHEMBL309329 | — | — | 1 | - |
| CHEMBL3221178 | — | — | 1 | - |
| CHEMBL75164 | — | — | 1 | - |
| CHEMBL306276 | — | — | 1 | - |
| CHEMBL2043424 | — | — | 1 | - |
| CHEMBL3221179 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2115165 | — | IC50 | = | 8900.0 | nM | 5.05 |
| CHEMBL3221177 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL309329 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3221178 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL75164 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL306276 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL2043424 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3221179 | — | IC50 | > | 50000.0 | nM | - |