Assay Detail
Functional
CHEMBL3225192
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Cytotoxicity against human HuCCa1 cells after 48 hrs by XTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HuCC-A1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Progress on lamellarins
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.45 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3218975 | — | — | 1 | 8.22 |
| CHEMBL301226 | — | — | 1 | 8.10 |
| CHEMBL3218977 | — | — | 1 | 7.40 |
| CHEMBL3218976 | — | — | 1 | 7.22 |
| CHEMBL3218978 | — | — | 1 | 7.16 |
| CHEMBL373114 | LAMELLARIN D | — | 1 | 7.10 |
| CHEMBL3218733 | — | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3218975 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL301226 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL3218977 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL3218976 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL3218978 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL373114 | LAMELLARIN D | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL3218733 | — | IC50 | = | 120.0 | nM | 6.92 |