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Assay Detail

CHEMBL3226687

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to serotonin 5-HT2B receptor (unknown origin) by PDSP assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2B (CHEMBL1833)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The synthesis and receptor binding affinities of DDD-016, a novel, potential, atypical antipsychotic
Bandyopadhyaya A, Rajagopalan DR, Rath NP, Herrold A, Rajagopalan R, Napier TC, Tedford CE, Rajagopalan P
Medchemcomm (2012) 3 : 580 -583
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.30 8.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3217984 1 8.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3217984 Ki = 5.012 nM 8.30