Assay Detail
Functional
CHEMBL3226861
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of LPS-induced TNFalpha production in human whole blood
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Blood |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Monocyte and macrophage selective anti-inflammatory kinase inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.17 | 7.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3220550 | — | — | 1 | 7.54 |
| CHEMBL3220549 | — | — | 1 | 7.24 |
| CHEMBL3220548 | — | — | 1 | 6.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3220550 | — | IC50 | = | 28.8 | nM | 7.54 |
| CHEMBL3220549 | — | IC50 | = | 57.5 | nM | 7.24 |
| CHEMBL3220548 | — | IC50 | = | 181.8 | nM | 6.74 |