Assay Detail
Functional
CHEMBL3227429
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Cytotoxicity against human H460 cells after 72 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H460 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Relative impact of 3- and 5-hydroxyl groups of cytosporone B on cancer cell viability.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.99 | 5.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3218048 | — | — | 1 | 5.34 |
| CHEMBL1221517 | CYTOSPORONE B | — | 1 | 4.82 |
| CHEMBL3218046 | — | — | 1 | 4.80 |
| CHEMBL3218047 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3218048 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL1221517 | CYTOSPORONE B | IC50 | = | 15300.0 | nM | 4.82 |
| CHEMBL3218046 | — | IC50 | = | 15900.0 | nM | 4.80 |
| CHEMBL3218047 | — | IC50 | > | 20000.0 | nM | - |