Assay Detail
Binding
CHEMBL3238922
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO-K1 cells by liquid scintillation counting
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO-K1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.13 | 9.19 |
| EC50 | 2 | 9.17 | 9.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3234698 | — | — | 1 | 9.33 |
| CHEMBL1668519 | — | — | 1 | 9.19 |
| CHEMBL3234699 | — | — | 1 | 9.00 |
| CHEMBL3234700 | — | — | 1 | 8.79 |
| CHEMBL3234708 | — | — | 1 | 8.17 |
| CHEMBL495528 | — | — | 1 | 6.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3234698 | — | EC50 | = | 0.47 | nM | 9.33 |
| CHEMBL1668519 | — | Ki | = | 0.64 | nM | 9.19 |
| CHEMBL3234699 | — | EC50 | = | 1.0 | nM | 9.00 |
| CHEMBL3234700 | — | Ki | = | 1.63 | nM | 8.79 |
| CHEMBL3234708 | — | Ki | = | 6.8 | nM | 8.17 |
| CHEMBL495528 | — | Ki | = | 422.0 | nM | 6.38 |