Assay Detail
Binding
CHEMBL3240887
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of cathepsin B in goat liver using alpha-N-benzoyl-D,L-arginine-2-naphthylamide as substrate by colorimetric analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Capra hircus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Acyl hydrazides and triazoles as novel inhibitors of mammalian cathepsin B and cathepsin H.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.75 | 6.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1588015 | — | — | 1 | 6.19 |
| CHEMBL339003 | — | — | 1 | 6.06 |
| CHEMBL3237995 | — | — | 1 | 5.87 |
| CHEMBL124267 | — | — | 1 | 5.72 |
| CHEMBL3237776 | — | — | 1 | 4.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1588015 | — | Ki | = | 640.0 | nM | 6.19 |
| CHEMBL339003 | — | Ki | = | 870.0 | nM | 6.06 |
| CHEMBL3237995 | — | Ki | = | 1360.0 | nM | 5.87 |
| CHEMBL124267 | — | Ki | = | 1900.0 | nM | 5.72 |
| CHEMBL3237776 | — | Ki | = | 12700.0 | nM | 4.90 |