Assay Detail
Functional
CHEMBL3242689
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human C8146A cells assessed as growth inhibition
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | C8146A |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Some non-conventional biomolecular targets for diamidines. A short survey.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.08 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL55 | PENTAMIDINE | 4.0 | 1 | 5.92 |
| CHEMBL185802 | — | — | 1 | 5.10 |
| CHEMBL364410 | — | — | 1 | 4.92 |
| CHEMBL187059 | — | — | 1 | 4.36 |
| CHEMBL434915 | — | — | 1 | - |
| CHEMBL365434 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL55 | PENTAMIDINE | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL185802 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL364410 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL187059 | — | IC50 | = | 44000.0 | nM | 4.36 |
| CHEMBL434915 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL365434 | — | IC50 | > | 100000.0 | nM | - |