Assay Detail
Functional
CHEMBL3243189
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Cytotoxicity against human HL60 cells after 24 hrs by WST-1 assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic constituents from Lobaria scrobiculata and a comparison of two bioassays for their evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.27 | 5.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL367881 | (+)-USNIC ACID | — | 1 | 5.27 |
| CHEMBL173530 | STICTIC ACID | — | 1 | - |
| CHEMBL3234666 | — | — | 1 | - |
| CHEMBL229087 | — | — | 1 | - |
| CHEMBL3234667 | — | — | 1 | - |
| CHEMBL3234668 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL367881 | (+)-USNIC ACID | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL173530 | STICTIC ACID | IC50 | > | 10000.0 | nM | - |
| CHEMBL3234666 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL229087 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3234667 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3234668 | — | IC50 | > | 10000.0 | nM | - |