Assay Detail
Functional
CHEMBL3253724
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Antiallergic activity in rat peritoneal mast cells assessed as inhibition of ovalbumin-induced histamine release after 15 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | Mast cell |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiallergy activity of substituted 11-oxo-11 H-pyrido[2,1-b]quinazoline-8-carboxylic acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.85 | 6.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL22336 | DOXANTRAZOLE | — | 1 | 6.32 |
| CHEMBL165674 | — | — | 1 | 6.03 |
| CHEMBL74 | CROMOLYN SODIUM | 4.0 | 1 | 5.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL22336 | DOXANTRAZOLE | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL165674 | — | IC50 | = | 940.0 | nM | 6.03 |
| CHEMBL74 | CROMOLYN SODIUM | IC50 | = | 6500.0 | nM | 5.19 |