Assay Detail
Functional
CHEMBL3257152
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Antivasopressor activity in iv dosed phenoxybenzamine treated rat assessed as antagonist activity on arginine-vasopressin-induced effect
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
[1-(beta-mercapto-beta,beta-cyclopentamethylenepropionic acid),4-valine,-8-D-arginine]vasopressin, a potent and selective inhibitor of the vasopressor response to arginine-vasopressin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.51 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3249156 | — | — | 1 | 7.82 |
| CHEMBL2370974 | — | — | 1 | 7.68 |
| CHEMBL435323 | — | — | 1 | 7.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3249156 | — | Kd | = | 15.14 | nM | 7.82 |
| CHEMBL2370974 | — | Kd | = | 20.89 | nM | 7.68 |
| CHEMBL435323 | — | Kd | = | 93.33 | nM | 7.03 |