Assay Detail
Functional
CHEMBL3267775
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Antimicrobial activity against Bacillus subtilis subsp. subtilis ATCC 6051 after 12 to 16 hrs by microbroth dilution method
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bacillus subtilis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Multitarget drug discovery for tuberculosis and other infectious diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 4.75 | 5.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3261890 | — | — | 1 | 5.27 |
| CHEMBL3261889 | — | — | 1 | 5.13 |
| CHEMBL3261884 | — | — | 1 | 5.07 |
| CHEMBL3261883 | — | — | 1 | 5.06 |
| CHEMBL561057 | SQ109 | 2.0 | 1 | 4.64 |
| CHEMBL3261880 | — | — | 1 | 4.32 |
| CHEMBL3261886 | — | — | 1 | 4.31 |
| CHEMBL3261888 | — | — | 1 | 4.21 |
| CHEMBL3261881 | — | — | 1 | - |
| CHEMBL3261882 | — | — | 1 | - |
| CHEMBL3261885 | — | — | 1 | - |
| CHEMBL3261887 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3261890 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL3261889 | — | IC50 | = | 7400.0 | nM | 5.13 |
| CHEMBL3261884 | — | IC50 | = | 8600.0 | nM | 5.07 |
| CHEMBL3261883 | — | IC50 | = | 8700.0 | nM | 5.06 |
| CHEMBL561057 | SQ109 | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL3261880 | — | IC50 | = | 48000.0 | nM | 4.32 |
| CHEMBL3261886 | — | IC50 | = | 49000.0 | nM | 4.31 |
| CHEMBL3261888 | — | IC50 | = | 62000.0 | nM | 4.21 |
| CHEMBL3261881 | — | IC50 | = | 199000.0 | nM | - |
| CHEMBL3261882 | — | IC50 | = | 199000.0 | nM | - |
| CHEMBL3261885 | — | IC50 | = | 200000.0 | nM | - |
| CHEMBL3261887 | — | IC50 | = | 198000.0 | nM | - |