Assay Detail
Functional
CHEMBL3268977
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at MT2 receptor (unknown origin) assessed as cAMP accumulation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.57 | 8.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL187525 | — | — | 1 | 8.01 |
| CHEMBL187593 | — | — | 1 | 7.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL187525 | — | IC50 | = | 9.7 | nM | 8.01 |
| CHEMBL187593 | — | IC50 | = | 76.0 | nM | 7.12 |