Assay Detail
Binding
CHEMBL3268980
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]2-iodomelatonin from MT2 receptor (unknown origin) expressed in HEK293 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.91 | 10.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL329263 | — | — | 1 | 10.30 |
| CHEMBL329086 | — | — | 1 | 9.96 |
| CHEMBL33549 | — | — | 1 | 9.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL329263 | — | Ki | = | 0.05 | nM | 10.30 |
| CHEMBL329086 | — | Ki | = | 0.11 | nM | 9.96 |
| CHEMBL33549 | — | Ki | = | 0.33 | nM | 9.48 |