Assay Detail
Binding
CHEMBL3268985
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]2-iodomelatonin from human recombinant MT2 receptor expressed in mouse NIH3T3 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | NIH3T3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.80 | 10.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL10009 | — | — | 1 | 10.30 |
| CHEMBL274438 | — | — | 1 | 9.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL10009 | — | Ki | = | 0.05 | nM | 10.30 |
| CHEMBL274438 | — | Ki | = | 0.5 | nM | 9.30 |