Assay Detail
ADMET
CHEMBL3269008
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Cytotoxicity against human MCF7 cells assessed as growth inhibition by MTT assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Multitarget drug discovery for tuberculosis and other infectious diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 4.80 | 5.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3261890 | — | — | 1 | 5.41 |
| CHEMBL3261884 | — | — | 1 | 5.19 |
| CHEMBL3261883 | — | — | 1 | 5.01 |
| CHEMBL561057 | SQ109 | 2.0 | 1 | 4.75 |
| CHEMBL3261889 | — | — | 1 | 4.66 |
| CHEMBL3261888 | — | — | 1 | 4.64 |
| CHEMBL3261886 | — | — | 1 | 4.57 |
| CHEMBL3261880 | — | — | 1 | 4.52 |
| CHEMBL3261885 | — | — | 1 | 4.46 |
| CHEMBL3261881 | — | — | 1 | - |
| CHEMBL3261882 | — | — | 1 | - |
| CHEMBL3261887 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3261890 | — | IC50 | = | 3900.0 | nM | 5.41 |
| CHEMBL3261884 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL3261883 | — | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL561057 | SQ109 | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL3261889 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL3261888 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL3261886 | — | IC50 | = | 27000.0 | nM | 4.57 |
| CHEMBL3261880 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL3261885 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL3261881 | — | IC50 | = | 338000.0 | nM | - |
| CHEMBL3261882 | — | IC50 | = | 220000.0 | nM | - |
| CHEMBL3261887 | — | IC50 | = | 178000.0 | nM | - |