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Assay Detail

CHEMBL3269227

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ADMET
Antiproliferative activity against human EPC cells after 72 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type EPC
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Design, synthesis and biological evaluation of Pontin ATPase inhibitors through a molecular docking approach.
Elkaim J, Lamblin M, Laguerre M, Rosenbaum J, Lestienne P, Eloy L, Cresteil T, Felpin FX, Dessolin J.
Bioorg Med Chem Lett (2014) 24 : 2512 -2516
PubMed 24767849 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.60 4.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3263107 1 4.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3263107 IC50 = 25000.0 nM 4.60