Assay Detail
Binding
CHEMBL3269820
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
In Vitro Membrane Permeation Studies and in Vivo Antinociception of Glycosylated Dmt(1)-DALDA Analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 9.27 | 9.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3264361 | — | — | 1 | 9.95 |
| CHEMBL2181202 | — | — | 1 | 9.85 |
| CHEMBL3264360 | — | — | 1 | 9.69 |
| CHEMBL3264359 | — | — | 1 | 9.65 |
| CHEMBL3264362 | — | — | 1 | 9.54 |
| CHEMBL60444 | — | — | 1 | 8.77 |
| CHEMBL3264358 | — | — | 1 | 7.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3264361 | — | Ki | = | 0.112 | nM | 9.95 |
| CHEMBL2181202 | — | Ki | = | 0.143 | nM | 9.85 |
| CHEMBL3264360 | — | Ki | = | 0.203 | nM | 9.69 |
| CHEMBL3264359 | — | Ki | = | 0.222 | nM | 9.65 |
| CHEMBL3264362 | — | Ki | = | 0.286 | nM | 9.54 |
| CHEMBL60444 | — | Ki | = | 1.69 | nM | 8.77 |
| CHEMBL3264358 | — | Ki | = | 38.4 | nM | 7.42 |