Assay Detail
Functional
CHEMBL3269981
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against BVDV AV-69 infected in MDBK cells assessed as cytopathic effect after 3 to 4 days by plaque reduction assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bovine viral diarrhea virus 1 |
| Cell Type | MDBK |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Bovine viral diarrhea virus 1 (CHEMBL612571) ↗| Type | ORGANISM |
| Organism | Bovine viral diarrhea virus 1 |
Publication
Synthesis and anti-BVDV activity of novel δ-sultones in vitro: implications for HCV therapies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 12 | 6.24 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3264944 | — | — | 1 | 6.92 |
| CHEMBL3264948 | — | — | 1 | 6.30 |
| CHEMBL3264943 | — | — | 1 | 6.30 |
| CHEMBL3264942 | — | — | 1 | 6.30 |
| CHEMBL3264949 | — | — | 1 | 6.00 |
| CHEMBL3264945 | — | — | 1 | 6.00 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 5.89 |
| CHEMBL3264947 | — | — | 1 | - |
| CHEMBL3264950 | — | — | 1 | - |
| CHEMBL3264946 | — | — | 1 | - |
| CHEMBL3264940 | — | — | 1 | - |
| CHEMBL3264941 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3264944 | — | EC50 | = | 120.0 | nM | 6.92 |
| CHEMBL3264948 | — | EC50 | = | 500.0 | nM | 6.30 |
| CHEMBL3264943 | — | EC50 | = | 500.0 | nM | 6.30 |
| CHEMBL3264942 | — | EC50 | = | 500.0 | nM | 6.30 |
| CHEMBL3264949 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3264945 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL3264947 | — | EC50 | > | 1200.0 | nM | - |
| CHEMBL3264950 | — | EC50 | > | 1200.0 | nM | - |
| CHEMBL3264946 | — | EC50 | > | 1200.0 | nM | - |
| CHEMBL3264940 | — | EC50 | > | 1200.0 | nM | - |
| CHEMBL3264941 | — | EC50 | > | 1200.0 | nM | - |