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Assay Detail

CHEMBL3270174

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Competitive inhibition of rat FAAH by Lineweaver-Burk plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Fatty-acid amide hydrolase 1 (CHEMBL3229)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

α-Ketoheterocycle inhibitors of fatty acid amide hydrolase: exploration of conformational constraints in the acyl side chain.
Duncan KK, Otrubova K, Boger DL.
Bioorg Med Chem (2014) 22 : 2763 -2770
PubMed 24690529 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL39412 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL39412 Ki = 100.0 nM 7.00