Assay Detail

CHEMBL3270646

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Functional

Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay

ChEMBL ↗

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Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Open DB target context

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NON-PROTEIN TARGET (CHEMBL3879801) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target NON-PROTEIN TARGET

CHEMBL3879801

Anchored from Assay target.

Protein identity NON-PROTEIN TARGET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	Huh-7
Confidence	1 — Organism
Curated By	Autocuration

Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Type	NON-MOLECULAR

Publication

Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption.

Hsiao CJ, Hsiao G, Chen WL, Wang SW, Chiang CP, Liu LY, Guh JH, Lee TH, Chung CL.
J Nat Prod (2014) 77 : 758 -765
PubMed 24588135 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.33	5.33

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL463175	CEPHALOCHROMIN	—	1	5.33

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL463175	CEPHALOCHROMIN	IC50	=	4640.0	nM	5.33