Assay Detail
Binding
CHEMBL3271319
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Inhibition of human recombinant SYK by HTRF assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Phenyl carboxamide analogues as spleen tyrosine kinase (syk) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 8.55 | 8.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3260318 | — | — | 1 | 8.55 |
| CHEMBL3260319 | — | — | 1 | - |
| CHEMBL3260320 | — | — | 1 | - |
| CHEMBL3260321 | — | — | 1 | - |
| CHEMBL3260322 | — | — | 1 | - |
| CHEMBL3260323 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3260318 | — | IC50 | = | 2.8 | nM | 8.55 |
| CHEMBL3260319 | — | IC50 | < | 1.5 | nM | - |
| CHEMBL3260320 | — | IC50 | < | 1.5 | nM | - |
| CHEMBL3260321 | — | IC50 | < | 1.5 | nM | - |
| CHEMBL3260322 | — | IC50 | < | 1.5 | nM | - |
| CHEMBL3260323 | — | IC50 | > | 1.5 | nM | - |