Assay Detail
Binding
CHEMBL3271433
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain cerebellum membrane
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Tissue | Cerebellum |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel delta opioid receptor agonists with oxazatricyclodecane structure.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 8.65 | 9.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3264742 | — | — | 1 | 9.50 |
| CHEMBL3264747 | — | — | 1 | 9.27 |
| CHEMBL13470 | SNC-80 | — | 1 | 8.98 |
| CHEMBL3264748 | — | — | 1 | 8.94 |
| CHEMBL3264745 | — | — | 1 | 8.91 |
| CHEMBL3264743 | — | — | 1 | 8.71 |
| CHEMBL3264746 | — | — | 1 | 8.59 |
| CHEMBL3264744 | — | — | 1 | 8.15 |
| CHEMBL3264741 | — | — | 1 | 6.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3264742 | — | Ki | = | 0.313 | nM | 9.50 |
| CHEMBL3264747 | — | Ki | = | 0.534 | nM | 9.27 |
| CHEMBL13470 | SNC-80 | Ki | = | 1.04 | nM | 8.98 |
| CHEMBL3264748 | — | Ki | = | 1.16 | nM | 8.94 |
| CHEMBL3264745 | — | Ki | = | 1.23 | nM | 8.91 |
| CHEMBL3264743 | — | Ki | = | 1.94 | nM | 8.71 |
| CHEMBL3264746 | — | Ki | = | 2.59 | nM | 8.59 |
| CHEMBL3264744 | — | Ki | = | 7.0 | nM | 8.15 |
| CHEMBL3264741 | — | Ki | = | 174.6 | nM | 6.76 |