Assay Detail
Binding
CHEMBL3291700
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Binding affinity to IL-2 (unknown origin)
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Prediction of anti-tumor chemical probes of a traditional Chinese medicine formula by HPLC fingerprinting combined with molecular docking.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 8 | 7.40 | 10.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL395414 | DISOGLUSIDE | 2.0 | 1 | 10.54 |
| CHEMBL3289607 | — | — | 1 | 8.59 |
| CHEMBL233929 | GALUTEOLIN | — | 1 | 7.70 |
| CHEMBL3289608 | — | — | 1 | 7.45 |
| CHEMBL3289611 | — | — | 1 | 7.26 |
| CHEMBL465980 | ONONIN | — | 1 | 6.92 |
| CHEMBL486422 | DAIDZIN | — | 1 | 5.47 |
| CHEMBL242341 | FORMONONETIN | 2.0 | 1 | 5.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL395414 | DISOGLUSIDE | Kd | = | 0.0289 | nM | 10.54 |
| CHEMBL3289607 | — | Kd | = | 2.59 | nM | 8.59 |
| CHEMBL233929 | GALUTEOLIN | Kd | = | 20.0 | nM | 7.70 |
| CHEMBL3289608 | — | Kd | = | 35.6 | nM | 7.45 |
| CHEMBL3289611 | — | Kd | = | 54.9 | nM | 7.26 |
| CHEMBL465980 | ONONIN | Kd | = | 120.0 | nM | 6.92 |
| CHEMBL486422 | DAIDZIN | Kd | = | 3380.0 | nM | 5.47 |
| CHEMBL242341 | FORMONONETIN | Kd | = | 5470.0 | nM | 5.26 |