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Assay Detail

CHEMBL3292866

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Influenza A virus (A/California/07/2009(H1N1)) infected in MDCK cells treated with 5 uM of compound measured after 2 passages by fluorescence-based miniplaque assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus (A/California/07/2009(H1N1))
Cell Type MDCK
Confidence 1 — Organism
Curated By Autocuration

Publication

Aminoadamantanes with persistent in vitro efficacy against H1N1 (2009) influenza A.
Kolocouris A, Tzitzoglaki C, Johnson FB, Zell R, Wright AK, Cross TA, Tietjen I, Fedida D, Busath DD.
J Med Chem (2014) 57 : 4629 -4639
PubMed 24793875 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.43 5.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1170182 1 5.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1170182 EC50 = 3700.0 nM 5.43