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Assay Detail

CHEMBL3293209

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]LSD from human 5-HT2B receptor by PDSP assay
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2B (CHEMBL1833)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Identification of a new selective dopamine D4 receptor ligand.
Sampson D, Zhu XY, Eyunni SV, Etukala JR, Ofori E, Bricker B, Lamango NS, Setola V, Roth BL, Ablordeppey SY.
Bioorg Med Chem (2014) 22 : 3105 -3114
PubMed 24800940 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.33 7.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3289656 2 7.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3289656 Ki = 47.0 nM 7.33
CHEMBL3289656 Ki = 46.77 nM 7.33